24,718 research outputs found

    Water as an economic good: a solution, or a problem ?

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    Water resource management / Economic aspects / Economic analysis / Irrigated farming / Water rights / Pricing / Privatization / Marginal analysis / Water market / Water policy

    New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction

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    ObjectivesLegg–Calvé–Perthes’ disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old. The factors that lead to the onset of LCP are still unclear; however, it is believed that interruption of the blood supply to the developing epiphysis is an important factor in the development of the condition.MethodsFinite element analysis modelling of the blood supply to the juvenile epiphysis was investigated to understand under which circumstances the blood vessels supplying the femoral epiphysis could become obstructed. The identification of these conditions is likely to be important in understanding the biomechanics of LCP.ResultsThe results support the hypothesis that vascular obstruction to the epiphysis may arise when there is delayed ossification and when articular cartilage has reduced stiffness under compression.ConclusionThe findings support the theory of vascular occlusion as being important in the pathophysiology of Perthes disease

    A pragmatic cluster randomized controlled trial of an educational intervention for GPs in the assessment and management of depression

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    Background. General practitioners (GPs) can be provided with effective training in the skills to manage depression. However, it remains uncertain whether such training achieves health gain for their patients. Method. The study aimed to measure the health gain from training GPs in skills for the assessment and management of depression. The study design was a cluster randomized controlled trial. GP participants were assessed for recognition of psychological disorders, attitudes to depression, prescribing patterns and experience of psychiatry and communication skills training. They were then randomized to receive training at baseline or the end of the study. Patients selected by GPs were assessed at baseline, 3 and 12 months. The primary outcome was depression status, measured by HAM-D. Secondary outcomes were psychiatric symptoms (GHQ-12) quality of life (SF-36), satisfaction with consultations, and health service use and costs. Results. Thirty-eight GPs were recruited and 36 (95%) completed the study. They selected 318 patients, of whom 189 (59%) were successfully recruited. At 3 months there were no significant differences between intervention and control patients on HAM-D, GHQ-12 or SF-36. At 12 months there was a positive training effect in two domains of the SF-36, but no differences in HAM-D, GHQ-12 or health care costs. Patients reported trained GPs as somewhat better at listening and understanding but not in the other aspects of satisfaction. Conclusions. Although training programmes may improve GPs' skills in managing depression, this does not appear to translate into health gain for depressed patients or the health service

    Will I? won't I? Why do men who have sex with men present for post-exposure prophylaxis for sexual exposures?

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    Background: Failures of post-exposure prophylaxis following sexual exposure (PEPSE) to prevent seroconversion have been reported and are often associated with ongoing risk exposure. Understanding why men who have sex with men (MSM) access PEPSE on some occasions and not others may lead to more effective health promotion and disease prevention strategies Methods: A qualitative study design using semi-structured interviews of 15 MSM within 6 months of them initiating PEPSE treatment at an HIV outpatient service in Brighton, UK. Results: PEPSE seeking was motivated by a number of factors: an episode that related to a particular sexual partner and their behaviour; the characteristics of the venue where the risk occurred; the respondent’s state of mind and influences of alcohol and recreational drug use; and their perceived beliefs on the effectiveness of PEPSE. Help was sought in the light of a “one-off” or “unusual” event. Many respondents felt they were less likely to behave in a risky manner following PEPSE. Conclusion: If PEPSE is to be effective as a public health measure, at risk individuals need to be empowered to make improved risk calculations from an increased perception that they could be exposed to HIV if they continue their current behaviour patterns. The concern is that PEPSE was sought by a low number of MSM implying that a greater number are not using the service based on failure to make accurate risk calculations or recognise high-risk scenario

    Indicators for comparing performance of irrigated agricultural systems

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    Irrigated farming / Irrigation systems / Indicators / Performance indexes / Financing / Crop production / Water demand / Water requirements / Prices

    Optical and Infrared Spectroscopy

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    Contains report on one research project.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E)U. S. Air Force (ESD Contract AF 19(628)-6066)M. I. T. Sloan Fund for Basic Researc

    Analytic Treatment of Positronium Spin Splittings in Light-Front QED

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    We study the QED bound-state problem in a light-front hamiltonian approach. Starting with a bare cutoff QED Hamiltonian, HBH_{_{B}}, with matrix elements between free states of drastically different energies removed, we perform a similarity transformation that removes the matrix elements between free states with energy differences between the bare cutoff, Λ\Lambda, and effective cutoff, \lam (\lam < \Lam). This generates effective interactions in the renormalized Hamiltonian, HRH_{_{R}}. These effective interactions are derived to order α\alpha in this work, with α1\alpha \ll 1. HRH_{_{R}} is renormalized by requiring it to satisfy coupling coherence. A nonrelativistic limit of the theory is taken, and the resulting Hamiltonian is studied using bound-state perturbation theory (BSPT). The effective cutoff, \lam^2, is fixed, and the limit, 0 \longleftarrow m^2 \alpha^2\ll \lam^2 \ll m^2 \alpha \longrightarrow \infty, is taken. This upper bound on \lam^2 places the effects of low-energy (energy transfer below \lam) emission in the effective interactions in the ee>| e {\overline e} > sector. This lower bound on \lam^2 insures that the nonperturbative scale of interest is not removed by the similarity transformation. As an explicit example of the general formalism introduced, we show that the Hamiltonian renormalized to O(α)O(\alpha) reproduces the exact spectrum of spin splittings, with degeneracies dictated by rotational symmetry, for the ground state through O(α4)O(\alpha^4). The entire calculation is performed analytically, and gives the well known singlet-triplet ground state spin splitting of positronium, 7/6α2Ryd7/6 \alpha^2 Ryd. We discuss remaining corrections other than the spin splittings and how they can be treated in calculating the spectrum with higher precision.Comment: 46 pages, latex, 3 Postscript figures included, section on remaining corrections added, title changed, error in older version corrected, cutoff placed in a windo

    Context Dependence, MOPs,WHIMs and procedures Recanati and Kaplan on Cognitive Aspects in Semantics

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    After presenting Kripke’s criticism to Frege’s ideas on context dependence of thoughts, I present two recent attempts of considering cognitive aspects of context dependent expressions inside a truth conditional pragmatics or semantics: Recanati’s non-descriptive modes of presentation (MOPs) and Kaplan’s ways of having in mind (WHIMs). After analysing the two attempts and verifying which answers they should give to the problem discussed by Kripke, I suggest a possible interpretation of these attempts: to insert a procedural or algorithmic level in semantic representations of indexicals. That a function may be computed by different procedures might suggest new possibilities of integrating contextual cognitive aspects in model theoretic semanti

    Photoluminescence Detected Doublet Structure in the Integer and Fractional Quantum Hall Regime

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    We present here the results of polarized magneto-photoluminescence measurements on a high mobility single-heterojunction. The presence of a doublet structure over a large magnetic field range (2>nu>1/6) is interpreted as possible evidence for the existence of a magneto-roton minima of the charged density waves. This is understood as an indication of strong electronic correlation even in the case of the IQHE limit.Comment: submitted to Solid State Communication
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